Endometriosis is at risk of causing epithelial ovarian cancer, here’s the explanation

Suara.com – Scientists have found a genetic link and a possible causal link between endometriosis and some types of ovarian cancer.

Endometriosis is a condition when cells similar to the lining of the uterus grow in other places, such as the fallopian tubes. This condition can cause severe pain to infertility in women.

It should be noted that endometriosis itself is not cancerous, but over the years researchers have compared the way endometriosis lesions metastasize, spread, invade, and damage tissue in the same way as cancer cells.

In this research researchers in Australia collected data from several genome association studies, report Science Alert.

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They found 19 genetic locations in the women’s DNA that appear to predispose them to endometriosis and make them susceptible to epithelial ovarian cancer (a type of cancer that develops in the outer layer of the ovaries).

illustration of a woman with a stomach ache (pixabay.com)
illustration of a woman with endometriosis (pixabay.com)

“Overall, the study estimates that 1 in 76 women are at risk of developing ovarian cancer in their lifetime, and the risk of developing endometriosis increases slightly to 1 in 55,” said biomolecular expert Sally Mortlock, from the University of Queensland, Australia.

Simply put, researchers found that the gene that causes endometriosis promotes the development of tissue that increases the risk of ovarian cancer.

These results suggest that endometriosis and epithelial ovarian cancer (EOC) are biologically related.

However, researchers don’t yet know how to predict which people with endometriosis are more likely to develop ovarian cancer.

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Even so, this research can be a reference in the development of potential drugs and treatment options for these two diseases.

The study was published in the journal Cell Reports Medicine.