Suara.com – Amid the BA1 and BA2 subvariants, the World Health Organization (WHO) said the Omicron variant also has a BA3 subvariance.
On March 5, 2022, Maria Van Kerkhove, Infectious Disease Epidemiologist and COVID-19 Technical Lead at the World Health Organization (WHO), said that there are similarities in the severity of the B2 and B1 subvariants with the BA3 subvariance of the Omicron variant.
Previously, Omicron variants included the Pango lineage B.1.1.529 and the Pango lineage BA1, BA.1.1, BA2 and BA3.
A research study published on January 18, 2022 in the Journal of Medical Virology has also confirmed the existence of the BA3 sub-lineage.
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“Our study found that there was no specific mutation for the BA3 lineage in the spike protein. Instead, it was a combination of mutations in the BA1 and BA2 spike proteins,” the study said. Times of India.
The study adds that the BA3 lineage was first detected in northwestern South Africa. Based on a study on January 11, 2022, of the total genome sequences submitted to the GISAID database, only 0.013 percent were Omicron’s BA3 subvariance and the highest was BA1.
“The BA3 subvariance is less common because it spreads at a very low rate and is less likely due to selecting six mutations (ins214EPE, S371L, G496S, T547K, N856K, and L981F) from BA1 or acquiring two mutations from BA.2 (S371F and D405N), said the research study.
Thus, the most dominant subvariants of the Omicron variant were BA1 and BA2, neither of which differed in severity.
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